Benefits of VIVE NAD+: A Key to Enhanced Well-being

VIVE NAD+ has emerged as a noteworthy supplement in the wellness arena. This blog explores its benefits and reasons for its growing popularity.

What is VIVE NAD+?

VIVE NAD+ is a form of NAD+ (nicotinamide adenine dinucleotide), a coenzyme presents in all living cells. It plays a crucial role in energy production and numerous cellular processes. VIVE NAD+ supplements aim to boost NAD+ levels in the body, which naturally decline with age.

Potential Health Benefits

a. Cancer and Cognitive Degeneration Prevention: NAD+ supplements may contribute to the prevention of cancer and cognitive degeneration, along with managing high cholesterol levels​​.

b. Healthy Aging: Studies suggest that NAD+ supplements can promote healthy aging. This includes improved energy levels, mental clarity, and alertness, all attributed to the positive effects on cellular processes that support cognitive function. There's also potential for improved memory and assistance in treating conditions like Alzheimer’s disease and dementia​​.

c. Skin Health: NAD+ aids in preserving genomic stability, crucial for maintaining skin health. The high turnover rate of skin cells benefits from the stability that NAD+ provides, helping to combat environmental damage like sun exposure​​.

d. Immune Function and Weight Management: Boosting NAD+ levels can help maintain immune function as we age. It also supports sirtuin activity, crucial for cellular function, potentially leading to increased energy and healthy weight management​​.

e. Enhanced Athletic Performance: The supplement has been linked to enhanced athletic performance and improved muscle function​​.

Why Use VIVE NAD+?

a. VIVE NAD+ treatment combines NAD+ is particularly effective for anti-aging, mental clarity, metabolic function, energy boost, performance improvement, and immune support​​.

b. Accessibility and Versatility: VIVE NAD+ is available for subcutaneous delivery in the comfort of your own home, making it easily accessible for different preferences and needs.

VIVE NAD+ presents a promising avenue for enhancing overall health and well-being. Its potential in promoting healthy aging, improving cognitive and skin health, boosting immune function, and enhancing athletic performance makes it a valuable addition to health regimens. As with any supplement, it’s advisable to consult with healthcare professionals before starting VIVE NAD+.

This is why we at Aesthetiverse® have selected VIVE NAD+ as our brand partner - it’s unique properties, service and advantages for Kinetic Aesthetic Pharmacy and our customers.

Dr. Mark Collins from Inside Out Biotech LTD made a report for the VIVE NAD+ supplement.

Here's the report:

"I have written what follows to give my personal opinion on why I am so passionate about the potential health benefits of taking subcutaneous ViveNad to raise the falling levels of NAD in our bodies as we grow older. I am a retired psychiatrist, with years of experience in hospital medicine before I switched to psychiatry. I have read numerous papers published in the academic journals about NAD so my opinion could reasonably be described as informed, but in no way is it an objective academic review. In the modern era almost all knowledge is available via the Internet so I would advise anyone reading this to check things out for themselves. I will attempt to keep medical jargon to a minimum, having said which, the next paragraph immediately uses a somewhat medical jargonish word.

Homeostasis, a word which describes how a system remains in balance whatever factors are tending to unbalance it, is the key to our ability to survive. The mechanisms ensuring homeostasis are extremely complex. Dealing with an infection provides a good example. An attack by a foreign invader, such as a bacterium, produces an inflammatory immune response which uses cellular and chemical activation to fight the enemy. Various signals tell the immune system where to send resources and which particular cells and chemicals are required. An equally important second system is there to clear up the mess and signal the inflammatory response to calm down, ensuring a return to homeostatic balance. Glitches may occur anywhere and when they are in the immune system, the result may be an autoimmune illness, of which there are a large number. These occur when the immune system mistakenly attacks cells in its host’s body. Common examples include Rheumatoid Arthritis and gut disorders such as Ulcerative Colitis. Many diseases commoner in old age result from too much inflammation in the body.

NAD is a vitally important part of the homeostatic process, particularly for repair and well-being of DNA along with healthy functioning of the mitochondria, the vital energy factories of every cell in which food energy is converted to cellular energy. The amount of NAD in each cell is of great importance. The lower the amount, the less effective is the protection of DNA. Also the mitochondria function less efficiently. The restoration of homeostasis becomes reduced. Unfortunately with every decade of our lives NAD levels fall by 10%. We are now recognising how so many diseases linked to older age, the neurodegenerative disorders, for example Alzheimer's Dementia, cardiovascular diseases, metabolic syndromes leading to Diabetes, are primarily caused by chronic inflammation, whatever secondary problems arise. The word ‘inflammaging’ has been coined to describe this. Recent research has shown that mitochondrial dysfunction may be an important but under-investigated part of why these diseases appear.

There is a very strong case from research in animals and humans to link the ageing process with the dropping levels of NAD, although there are obviously many other things involved too. This leads immediately to the idea that increasing NAD levels by whatever means might slow, or even reverse, some of the consequences of ageing. NAD is mostly made from vitamin B3, Niacin, which we get in our diets, some from Tryptophan, an amino acid. An insufficient quantity of Niacin causes a disease called Pellagra which damages the skin, the intestines and the brain, ultimately causing death.

There are essentially three ways to elevate the levels of NAD available to the cells. The simplest practical way, thus the one that has been most studied, is to give it by mouth. NAD itself, a chemically fragile molecule, is destroyed in the gut and therefore is not an option. However there are several chemical precursors of NAD, which are converted into NAD once absorbed and are the ones that have been studied. Niacin itself, in high dose, can be used and the other two common precursors are NR and NMN. At the other extreme, NAD itself can be introduced directly into the bloodstream by intravenous infusions, thus avoiding the hazards of the journey through the gut. Both of these methods have been used for a number of years but both have significant disadvantages. 

It is always uncertain when something is taken by mouth how much will actually be absorbed into the body. Many factors may influence this, such as gender, age, presence of illness, obesity, the overall health or otherwise of the gut microbiome to name a few. The intravenous route guarantees direct access into the bloodstream. However it is a long, laborious and rather unpleasant process which requires an intravenous drip, monitoring over several hours by nurses and quite often an extremely unpleasant set of side effects during the infusion.

ViveNad provides the perfect compromise. Instead of risking the uncertainty of oral absorption or the discomfort and time intensity of the intravenous route, ViveNad is administered at home in a process that takes about one minute, certainly way less time than it takes to brush ones teeth. It does involve a tiny injection which is administered subcutaneously (under the skin) where it is rapidly absorbed into the bloodstream. Although it is an injection, the sensation produced is far less than an insect sting and lasts for merely seconds. It is exactly the same process as a diabetic injecting insulin might use. We find that people usually get over their fears of an injection within a matter of days.

Research into the effects of raising NAD levels is still relatively new, most of it having been published over the last few years. However excitement at what scientists are discovering is skyrocketing. Much work has been done using animal models, the results of which are suggestive of what may happen in humans, but not wholly conclusive. Increasingly studies are taking place in humans and these are the ones causing most excitement. For practical reasons, many of the human studies have been done using the oral NAD precursors and although small numbers of participants are involved, no adverse side effects of any consequence have been shown and definitely some benefits particularly with NMN. Whether these benefits occur across the board, or more in people who are already healthy and well is unclear.

A fair number of human studies have been done using the intravenous route, with no adverts effects apart from the sometimes intolerable symptoms experienced during the actual infusion. However there are some theoretical reasons why too much NAD administered too quickly may not always be such a good thing. Subcutaneous NAD has the fewest actual human studies but equally, has many reasons to assume that it is likely to be the best route of administration, guaranteeing safe absorption with fewest side effects.

Rather than quoting from the numerous academic papers, some nearly incomprehensible to me despite my extensive medical and scientific background, I thought instead I would share my own personal experience as a consumer of NAD. I first came across NAD about 10 years ago. At the time I was a busy psychiatrist with a particular interest in treating patients with addictive disorders. Via a friend I was able to witness the outcome of patients treated at a clinic which was using intravenous NAD infusions for severe alcoholism. I vaguely remembered what NAD was, from my preclinical university lectures in biochemistry, but could not see any way in which it could be of use in treating alcoholism. I arrived at the clinic with a large dollop of scepticism, assuming that at best I might witness a bit of hocus-pocus and placebo effect. I was astounded by what I did see.

Time and again I observed patients with severe alcohol dependency or sedative prescription drug dependency being detoxified with virtually no side effects whatsoever and not appearing to require any of the medication predicated by conventional orthodox medicine. To give one of many examples, I followed the progress of a man with a decades long history of severe alcohol dependency, drinking at least a bottle of vodka per day over many years. In the past he had experienced episodes of Delirium Tremens (DTs) when trying to stop, something very serious, possibly lethal. Conventionaltreatment would have required around ten days in hospital with very large doses of diazepam (Valium) in a decreasing dose regime, perhaps as much as 200 mgs on the first day. This patient had a grand total of one 5 mg Diazepam tablet on the first day, nothing at all thereafter, and with daily NAD infusions, completely detoxified from alcohol with not a single symptom of withdrawal. I could give numerous other examples. I then read up about NAD and discovered much interest about the potential benefits of NAD administration, most of it at that time based on studies in animals and various case reports in humans.

In 2015 I had a severe medical problem and during a thirteen hour operation to replace my thoracic aortic arch, I suffered total paralysis of the left side of my body. The neurologists who saw me shook their heads and predicted that I would be unlikely to recover more than a fraction of normal function. Having learned from reading about NAD of its putative benefits for brain cells, I embarked on a series of intravenous infusions of NAD. Results in one person of course prove nothing at all on their own but my recovery was 85 to 90%, far more than predicted by the experts.

More recently, at the beginning of the pandemic, I caught Covid and was severely ill with pneumonia and afterwards suffered from what became known as Long Covid. My main symptoms were ‘brain fog’, where my thought processes were slower and less efficient than usual, and severe muscle fatigue when walking. A one hundred yard walk to the shops left me feeling I had run a marathon. I tried an evidence based treatment using hyperbaric oxygen, but this only brought about 20% improvement. It then occurred to me that, however Covid had made it happen, the muscle fatigue might in some way result from poorly functioning mitochondria in the muscle cells, the mitochondria being the cells’ energy factories. The role of NAD in healthy functioning of mitochondria was by now well established. 

I had previously tried all the various oral tablet ways of raising NAD levels, high dose Niacin, NMN and NR. None had made any difference to anything pre- or post-Covid. I could not face the ordeal or expense of going through multiple intravenous infusions again. By good fortune I learned that subcutaneous NAD had just come to the market so I decided to try it. Again, the result in one patient (me) proves nothing, but I was astonished by my experience, 100% resolution of my Long Covid symptoms within two weeks, which has been sustained ever since.

Since then I have seen the effects of ViveNad in many dozens of people and almost all report similar effects. Whatever their initial state, after a period of time, sometimes just a short number of weeks, they report feeling more energetic, their brains are sharper and more focused, they look and feel better, dare I say they feel younger! Indeed the Inside Out company which produces ViveNad was started essentially on the back of the founders’ (I am one) subjective experience of taking subcutaneous NAD themselves. We noted the increasing volume of scientific support for the simple idea that the ageing process is linked to the gradual breakdown of homeostatic mechanisms which prevent the inflammatory process, so vital to our survival when fighting off pathogens, getting out of control. More and more, the myriad diseases associated with ageing are thought to derive from unbridled inflammation or, as I said earlier, inflammaging. This breakdown in homeostasis correlates well with the physical decline of our bodies and falling levels of NAD over the decades of our life.

I intend to take subcutaneous ViveNad for the rest of my life, which, if my beliefs are correct, should last longer than it otherwise would have."

Dr Mark Collins MA, MB, BS, MRCP, MRCPsych. August 2023 Retired Consultant Psychiatrist